Description_x000D_ Application_x000D_ 5-Methylcytosine hydrochloride has been used as standard in high performance liquid chromatography (HPLC) for the estimation of global methylation rates. It has also been used in high-resolution mass spectroscopic analysis._x000D_ 5-Methylcytosine is used in studies of DNA methylation processes (epigenetics)._x000D_ Packaging_x000D_ 1 g in poly bottle_x000D_ 250 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ 5-Methylcytosine mediates gene expression, genomic imprinting and inhibition of transposable elements. It is closely associated with translational fidelity and tRNA recognition.