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Description_x000D_
Immunogen_x000D_
Peptide sequence around aa. 574-578/575-579 (T-Y-Y-K-A), according to the protein PTK2._x000D_
Target description_x000D_
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity._x000D_
Physical form_x000D_
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol_x000D_
Features and Benefits_x000D_
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
- Related Categories Alphabetical Index, Antibodies, PT-PY, Primary Antibodies conjugate
