ANTI-SODIUM CHANNEL ASIC4

Description_x000D_ Immunogen_x000D_ peptide CKIKFAEEDAKPKEKEAGDE corresponding to residues 7-26 of N-terminal rat Accn4._x000D_ Target description_x000D_ Sodium Channel ASIC4 is a member of the ASIC family that also includes ASIC1, ASIC2 and ASIC3. The ASIC family is part of a large channel superfamily known as degenerin/epithelial sodium channels (DEG/ENaC). The functional ASIC channel is composed of 4 subunits, which can form either a homo or heterotetramer. ASIC4 protein does not appear to function as a proton-gated channel when expressed alone in heterologous systems and therefore a modulatory role for this subunit has been proposed. ASIC4 protein is expressed in brain, pituitary gland, spinal cord and inner ear._x000D_ Physical form_x000D_ Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide._x000D_ Reconstitution_x000D_ Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%)._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.