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Description_x000D_
Biochem/physiol Actions_x000D_
B355252 is a neuroprotective agent that potentiates nerve growth factor (NGF)-induced neurite outgrowth and protects against cell death caused by glutamate-evoked oxidative stress. In a murine hippocampal neuronal cell line, B355252 increased cell viability and protected against cell death caused by glutamate-induced toxicity, inhibiting glutamate-evoked increase in intracellular Ca2+ and ROS production._x000D_
Features and Benefits_x000D_
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
- Related Categories Antioxidants and Cytoprotectants, B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cell Stress, Nitric Oxide and Cell StressMore... Quality Level