GLUTATHIONE MONOETHYL ESTER 1PC X 50MG

Description General description Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Effective transport of GSH-MEE has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. A protective agent against cellular damage, such as cataracts and mitochondrial degeneration. Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration. Packaging 50 mg in Glass bottle Biochem/physiol Actions Cell permeable: no Primary Target Effective transport of GSH-MEE Product does not compete with ATP. Reversible: no Packaging Packaged under inert gas Warning Toxicity: Standard Handling (A) Reconstitution Following reconstitution, aliquot and freeze (-20°C). Unstable in solution; reconstitute just prior to use. Other Notes Grattagliano, I., et al. 1995. J. Pharmacol. Exp. Ther. 272, 484. Martensson, J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 317. Anderson, M.E., and Meister, A. 1989. Anal. Biochem. 183, 16. Anderson, M.E., et al. 1985. Arch. Biochem. Biophys. 239, 538. Wellner, V.P., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 4732. Puri, R.N., and Meister, A. 1983. Proc. Natl. Acad. Sci. USA 80, 5258.; Description