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Description_x000D_
General description_x000D_
Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients._x000D_
Application_x000D_
Histamine dihydrochloride has been used:_x000D_
• as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)_x000D_
• to determine its level in fish using HPLC (high performance liquid chromatography)_x000D_
• to assess the tracheal response to antigens in guinea-pigs_x000D_
Packaging_x000D_
10 mg in glass bottle_x000D_
10, 25 g in poly bottle_x000D_
5 g in glass bottle_x000D_
Features and Benefits_x000D_
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm._x000D_
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_
Legal Information_x000D_
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
- Related Categories Agonists, Amino Acid, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, H, Histaminergics, Membrane Protein Biology Tools, Metabolic Pathways, Metabolites and Cofactors on the Metabolic Pathways Chart, Metabolomics, Mistaminergics - Agonists, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and DerivativesMore... Quality Level