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Description_x000D_
Application_x000D_
Interferon-γ human has been used:_x000D_
• to study the effect of interferon-γ on cultured trophoblasts in absence and presence of fibronectin_x000D_
• to analyse factors which participate in the production of antibody microarrays on glass support_x000D_
• for ELISA (enzyme-linked immunosorbent assay) method to understand the effect of interferon-γ in human gingival fibroblasts in presence of bacterial challenge_x000D_
Biochem/physiol Actions_x000D_
IFNG (interferon-γ) is a type-2 interferon which is produced by Th (T helper cells)-1 lymphocytes, CD8 cytotoxic lymphocytes, natural killer (NK) cells, and natural killer T (NKT) cells. It plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections. High expression of IFNG is common in many autoimmune diseases, such as systemic lupus erythematosis, Sjögren syndrome, inflammatory bowel disease and multiple sclerosis._x000D_
Physical form_x000D_
Lyophilized from phosphate buffered saline._x000D_
Analysis Note_x000D_
The biological activity is measured by a viral resistance assay.
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