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Description_x000D_
General description_x000D_
The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute)._x000D_
• Optimized and ready for transfection._x000D_
• Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets._x000D_
• Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects._x000D_
• Available as a whole human library and individual miRNA targets._x000D_
Other Notes_x000D_
This miRNA was removed from miRBase in release 18_x000D_
Legal Information_x000D_
MISSION is a registered trademark of Sigma-Aldrich Co. LLC
- Related Categories Functional Genomics and RNAi, Molecular Biology, miRNA, miRNA mimics
