Description_x000D_ General description_x000D_ Subunit molecular weight: ~90,770_x000D_ Composed of six subunits with total molecular weight: ~544,620_x000D_ Urease is a cytosolic enzyme that catalyzes the hydrolysis of urea to ammonia and carbon dioxide, with initial conversion to carbamate, and the carbamate breaks down further, on hydrolysis, into ammonia and to carbonic acid / carbonate. Urease is a metalloenzyme that contains nickel as a co-factor. Urease occurs naturally in plants, fungi, and certain bacteria. James B. Sumner first isolated urease from jack bean in 1926._x000D_ Packaging_x000D_ 20000, 100000, 500000, 1000000 units in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Urease from Canavalia ensiformis functions as an insecticide by the release of a toxic small peptide cleaved by proteases found in the gut of insects._x000D_ Unit Definition_x000D_ One micromolar unit will liberate 1.0 μmole of NH3 from urea per min at pH 7.0 at 25 °C. It is equivalent to 1.0 I.U. or 0.054 Sumner unit (1.0 mg ammonia nitrogen in 5 minutes at pH 7.0 at 20 °C)