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Description
General description
1-Methylindole-2-carboxylic acid reacts with thionyl chloride to yield sulfinyl chlorides.
Application
• Reactant for preparation of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors
• Reactant for synthesis of fenbufen and ethacrynic acid derivatives as potential antitumor agents via amide coupling reactions
• Reactant for diastereoselective synthesis of vinylated heterocycles via ruthenium-catalyzed oxidative vinylation with alkenes
• Reactant for synthesis of 2,3-dihalo indoles via hypervalent iodine mediated decarboxylative halogenation
• Reactant for preparation of α-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
• Reactant for preparation of anthranilic acid mimics as bacterial translation inhibitors
Packaging
1, 5 g in glass bottle
- Related Categories Building Blocks, C10, Chemical Synthesis, Heterocyclic Building Blocks, Indoles More... Quality Level