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Description_x000D_
General description_x000D_
α-Amylases are endoglycosidases, that are classified into glycosyl hydrolase family 13 (1-3)._x000D_
Application_x000D_
α-Amylase Inhibitor from Triticum aestivum (wheat seed) has been used to determine its effects on salivary gland (SG) amylase activity. It has also been used to inhibit the activity from the extract from Bemisia tabaci._x000D_
Packaging_x000D_
1, 5, 25 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
Competitive inhibitor of human salivary α-amylase. KI = 2.9 nM, compared to a KM of 5.9 mM (calculated per mole of α-1,4-linked maltose residues)._x000D_
α-Amylases can hydrolyze α-(1,4)-D-glycosidic linkages. It participates in the breakdown of starch and glycogen. Inhibiting this enzyme can be used as a strategy to treat dental caries, diabetes, obesity and periodontal diseases._x000D_
Unit Definition_x000D_
One unit will reduce the activity of two units of α-amylase (A0521) by 50% after pre-incubation at 25 °C._x000D_
Physical form_x000D_
Lyophilized powder containing buffer salts as sodium phosphate.
- Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates, ProteinsMore... Quality Level