ADENOSINE 5'-O-(2-THIODIPHOSPHATE)

Description_x000D_ Application_x000D_ Adenosine 5′-[β-thio]diphosphate is a substrate and inhibitor for AMP dependent enzyme systems. Adenosine 5′-[β-thio]diphosphate has been used to explore the myenteric control mechanisms of human esophageal motility and the effect of nitrergic and nonnitrergic neurotransmitters._x000D_ Adenosine 5′-[β-thio]diphosphate trilithium salt has been used to induce neuropathic pain in rats to study the effect of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors._x000D_ Biochem/physiol Actions_x000D_ P2Y receptor agonist._x000D_ Features and Benefits_x000D_ This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_ Other Notes_x000D_ Non-hydrolyzable ADP analog_x000D_ Substrates_x000D_ Substrate and inhibitor for AMP dependent enzyme systems.