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Description
General description
Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite.
Chemical structure: benzimidazole
Application
Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
10 g in poly bottle
Biochem/physiol Actions
Binds to tubulin and inhibits microtubule assembly.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A4673.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
- Related Categories Analytical Standards, Analytical/Chromatography, Antibiotics, Antibiotics A to Z, Antibiotics Standards, Antibiotics A-F, Antiparasitic / Antiprotozoal / Anthelminthic, Benzimidazoles, Biochemicals and Reagents, Chemical Structure Class, Pharmaceuticals, Illicit Drugs & Alcohol, Spectrum of Activity More... Quality Level
