ANTI-C1QL1

Description_x000D_ General description_x000D_ C1QL1 (complement component 1 Q subcomponent-like 1) gene is conserved among the vertebrates. C1QL1 codes for a multimeric protein with 258 amino acid polypeptide and a hydrophobic signal sequence. The encoded protein consists of a collagenous region and a globular domain. The gene is broadly expressed in brain, predominantly in the brainstem._x000D_ Immunogen_x000D_ C1QL1 (NP_006679.1, 1 a.a. ~ 258 a.a) full-length human protein._x000D_ Sequence_x000D_ MLLVLVVLIPVLVSSGGPEGHYEMLGTCRMVCDPYPARGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPGEKGEPGKPGPPGLPGAGGSGAISTATYTTVPRVAFYAGLKNPHEGYEVLKFDDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVILHLDAGDEVFIKLDGGKAHGGNSNKYSTFSGFIIYSD_x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.4_x000D_ Biochem/physiol Actions_x000D_ RNA editing of C1QL1 is found to cause non-synonymous amino acid substitutions. The proteins belonging to the C1q/TNF (complement component 1 Q subcomponent-like 1/ tumor necrosis factor) family are known to be associated with numerous systems such as immune, endocrine, skeletal, neuronal, reproductive, sensory, and vascular systems. CTRPs are involved in the regulation of glucose metabolism.