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Description_x000D_
General description_x000D_
Cyclin T2 (CCNT2) is the regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex. It is also called as positive transcription elongation factor B (P-TEFB)._x000D_
Immunogen_x000D_
Recombinant fragment corresponding to a region within amino acids 497 and 730 of cyclin T2 according to NP_490595_x000D_
Application_x000D_
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user._x000D_
Physical form_x000D_
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative._x000D_
Biochem/physiol Actions_x000D_
Cyclin T2 (CCNT2) is required as a cofactor and activator. It has roles in different cellular pathways such as transcriptional elongation, differentiation and apoptosis. CCNT2 phosphorylates the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II)._x000D_
Features and Benefits_x000D_
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
- Related Categories Alphabetical Index, Antibodies, CC-CC, Primary Antibodies conjugate