Anti-CINC-2 beta, Developed in goat

Description_x000D_ General description_x000D_ The neutrophil-attracting chemokines in rats are termed as cytokine-induced neutrophil chemoattractants (CINC). There are four CINC members, CINC-1, CINC-2α, CINC-2β and CINC-3. The CINC-2α and -2β members differ at the C-terminus. The members of CINC family signal through the CXCR2 receptor. The CINC members play a major role in recruitment of neutrophils in response to LPS into the rat lungs. Anti-CINC-2β antibody recognizes rat CINC-2β. It exhibits ~100% cross-reactivity with recombinant rat CINC-2α 50% cross-reactivity with mouse MIP-2, 35% cross-reactivity with mouse KC, 15% cross-reactivity with rat CINC-1, and 10% cross-reactivity with recombinant human IL-8, GROα, GROβ, and GROγ._x000D_ Specificity_x000D_ The antibody recognizes recombinant rat CINC-2β. It exhibits ~100% cross-reactivity with recombinant rat CINC-2α, 50% cross-reactivity with mouse MIP-2, 35% cross-reactivity with mouse KC, 15% cross-reactivity with rat CINC-1, and 10% cross-reactivity with recombinant human IL-8, GROα, GROβ, and GROγ._x000D_ Immunogen_x000D_ recombinant rat CINC-2β, expressed in E. coli._x000D_ Application_x000D_ Anti-CINC-2β antibody may be used for immunoblotting at a working antibody concentration of 0.1-0.2 μg/ml may be used. For ELISA, a working antibody concentration of 0.5-1.0 μg/ml is recommended._x000D_ Physical form_x000D_ Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.