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Description_x000D_
General description_x000D_
Anti-Collagen I α2 Antibody detects endogenous levels of total Collagen I α2 protein._x000D_
Collagen I α2 (COL1A2) is located on human chromosome 7q22.1. Human COL1A2 gene consists of two dinucleotide repeats: one in the 5′-flanking region of the gene, made of of poly(dC–dA) and poly(dC–dG) and the other in the first intron comprised of poly(dG–dT)._x000D_
Immunogen_x000D_
The antiserum was produced against synthesized peptide derived from human Collagen I alpha2._x000D_
Immunogen Range: 471-520_x000D_
Application_x000D_
Anti-Collagen I α2 antibody has been used to quantify protein expression levels after western blotting._x000D_
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below._x000D_
Immunohistochemistry (1 paper)_x000D_
Physical form_x000D_
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_
Disclaimer_x000D_
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_
Biochem/physiol Actions_x000D_
Collagen I α2 (COL1A2) is essential to maintain elasticity of the vessel wall and is an important constituent of the extracellular matrix. Mutations in COL1A2 results in osteogenesis imperfecta (OI)._x000D_
Features and Benefits_x000D_
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
- Related Categories Alphabetical Index, Antibodies, CO-CP, Primary Antibodies conjugate