Description_x000D_ General description_x000D_ The guanine nucleotide binding protein β3 (GNB3) gene is composed of 11 exons and 10 introns. It is the 3 subunit of heterotrimeric G-proteins located on human chromosome 12p13._x000D_ Immunogen_x000D_ Peptide with sequence SGHDNRVSCLGVT, from the internal region of the protein sequence according to NP_002066.1, NP_067642.1_x000D_ Physical form_x000D_ Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Guanine nucleotide binding protein 3 (GNB3) is involved in the conversion of external receptor activation signals into intracellular signals and it plays an important role in signal transduction pathways. It modulates and associates with favorable antidepressant response. GNB3 takes part in a variety of cellular processes like G protein-coupled receptor signaling._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.