Description_x000D_ General description_x000D_ G protein-coupled receptor 137B (GPR137B) is part of the G protein-coupled receptor superfamily. It is expressed in lysosomes. GPR137B is a 45kDa protein with 399 amino acids. It has four putative N-glycosylation sites and a potential dileucine-based lysosomal targeting signal. GPR137B mRNAs are expressed in the brain, heart, kidney and placenta. The gene encoding it is localized on human chromosome 1q42-q43._x000D_ Immunogen_x000D_ Synthetic peptide corresponding to a region within amino acids 335 and 399 of TM7SF1/GPR137B according to NP_003263_x000D_ Application_x000D_ Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user._x000D_ Physical form_x000D_ 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative._x000D_ Biochem/physiol Actions_x000D_ G protein-coupled receptor 137B (GPR137B) may be involved in signal transduction across lysosome membrane. An elevated level of the protein is observed during kidney development._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.