ANTI-IL-17 (AB1)

Description_x000D_ General description_x000D_ IL-17A (interleukin 17A) is a proinflammatory cytokine of Th17 (helper T cells). It is located on chromosome 6p12._x000D_ Immunogen_x000D_ a 16 amino acid peptide from near the amino-terminus of human IL-17A._x000D_ Application_x000D_ Anti-IL-17 has been used in western blotting and immunohistochemistry._x000D_ Physical form_x000D_ Solution in phosphate buffered saline containing 0.02% sodium azide_x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ IL-17A (interleukin 17A) plays a major role in the pathogenesis of autoimmune diseases like multiple sclerosis and rheumatoid arthritis. It also plays a pathogenic role in allergic rhinitis (AR). It helps in the formation of several chemokines and cytokines in airway epithelial cells._x000D_ Linkage_x000D_ The action of this antibody can be blocked using blocking peptide SBP4877.