ANTI-IL-23

Description_x000D_ General description_x000D_ IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3._x000D_ Immunogen_x000D_ IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23._x000D_ Application_x000D_ Anti-IL-23 antibody has been used in western blotting._x000D_ Physical form_x000D_ Supplied in PBS with 0.02% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more._x000D_ Linkage_x000D_ The action of this antibody can be blocked using blocking peptide SBP3500310.