Description_x000D_ Immunogen_x000D_ synthetic peptide corresponding to the N-terminal extracellular domain of human melanocortin 4 receptor. The immunizing peptide has 94% homology with the rat and mouse gene._x000D_ Physical form_x000D_ Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Melanocortin 4 receptor (MC4R) is an important regulator of food intake and body weight in mammals. It also regulates energy homeostasis in response to neuropeptides. Polymorphisms in MC4R gene or haploinsufficiency results in early onset obesity in humans also termed melanocortin obesity syndrome.