ANTI-MT-ND1

Description_x000D_ General description_x000D_ Anti-MT-ND1 Antibody detects endogenous levels of total MT-ND1 protein._x000D_ MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1._x000D_ Immunogen_x000D_ The antiserum was produced against synthesized peptide derived from human MT-ND1._x000D_ Immunogen Range: 176-225_x000D_ Physical form_x000D_ Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) plays a vital role in the electron transport chain of oxidative phosphorylation (OXPHOS). Mutations in MT-ND1 gene is observed in individuals with LHON (leber′s hereditary optic neuropathy). Mutation in MT-ND1 results in dextrocardia, ventriculoarterial discordance and tricuspid atresia._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.