Description_x000D_ General description_x000D_ The functional N-Methyl-D-Aspartate (NMDA) receptor complex consists of a NMDAR1 (NR1) subunit and atleast one NMDAR2 subunit ranging from NR2A-NR2D. These receptor complexes have been implicated in cochlear functions and neuronal plasticity. The C-terminal end of NR2B receptor may regulate synaptic localization_x000D_ Anti-Glutamate Receptor NMDAR2B (NR2B) antibody is specific for NR2B subunit in mice, rats and humans. This antibody does not react with NR2A or NR2C subunits. The labeling of NR2B subunit by immunoblotting is blocked by the preadsorption of the antibody with the immunogen._x000D_ Immunogen_x000D_ C-terminal portion of NR2B (amino acids 984-1104)._x000D_ Application_x000D_ Anti-Glutamate Receptor NMDAR2B (NR2B) antibody is suitable for use in immunohistochemistry (1:1,000 dilution, using frozen sections), immunoprecipitation (3 μL using 200 μg of rat brain), and indirect ELISA. The antibody may also be used for western blot (1 μg/mL using (35S)-Protein A) and immunoblot (180 kDa)._x000D_ Physical form_x000D_ Lyophilized from ammonium bicarbonate (5 mM)._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Packaging_x000D_ 10 μg in serum bottle