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Description_x000D_
Immunogen_x000D_
Peptide sequence around aa. 40-44 (E-E-Y-E-Q), according to the protein NFKBIA._x000D_
Target description_x000D_
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription._x000D_
Physical form_x000D_
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol_x000D_
Features and Benefits_x000D_
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
- Related Categories Alphabetical Index, Antibodies, NE-NI, Primary Antibodies conjugate