Description_x000D_ Immunogen_x000D_ Immunogen Sequence: GI # 21361405, sequence 41-100_x000D_ Recombinant regulator of G-protein signalling 17_x000D_ Application_x000D_ Anti-RGS17 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200._x000D_ Physical form_x000D_ Solution in phosphate buffered saline containing 0.02% sodium azide._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ Regulator of G-protein signaling 17 is a protein encoded by the RGS17 gene in humans and is mapped to chromosome 6q23-25. RGS17 encodes a member of the regulator of G-protein signaling RGS-Rz subfamily. It is differentially expressed in hepatocellular carcinoma (HCC) and plays a central role in regulating transformed hepatocyte tumorgenicity. RGS17 is over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.