ANTI-TRIM37 (C-TERMINAL)

Description_x000D_ Immunogen_x000D_ Synthetic peptide corresponding to a region within amino acids 902 and 964 of TRIM37 (Uniprot ID#O94972)_x000D_ Application_x000D_ Anti-TRIM37 (C-terminal) antibody produced in rabbit is suitable for immunocytochemistry, immunofluorescence, immunohistochemistry (formalin-fixed, paraffin-embedded sections) and western blot._x000D_ Physical form_x000D_ 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative._x000D_ Disclaimer_x000D_ Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals._x000D_ Biochem/physiol Actions_x000D_ TRIM37 (Tripartite motif containing 37) restricts centriole reduplication during centriole biogenesis. It participates in epigenetic transcriptional repression by facilitating monoubiquitination of ′Lys-119′ of histone H2A (H2AK119Ub). TRIM37 also possesses anti-HIV activity. Mutation in TRIm37 causes an autosomal recessive prenatal-onset growth disorder, mulibrey nanism with dysmorphic features, cardiomyopathy, and hepatomegaly._x000D_ Features and Benefits_x000D_ Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.