Description General description Effective concentration: 1-100 µM. Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain, and some cysteine proteases (IC50 ~500 ng/ml). Effective at concentrations of 1-100 µM. Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca2+-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC50 = 300 µM). Packaging 10 mg in Plastic ampoule 5 mg in Glass bottle Biochem/physiol Actions Cell permeable: no Primary Target Trypsin-like serine proteases Product does not compete with ATP. Reversible: no Target IC50: 300 µM against trypsin-like serine proteases, papain and some cysteine proteases Warning Toxicity: Standard Handling (A) Reconstitution Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C. Other Notes Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23. Umezawa, H. 1976. Methods Enzymol.55, 678.