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Description
General description
Forms dimers in aqueous solutions with an association constant of 5 × 104 M-1. The association is accompanied by an enhancement of ~35% in α-helical content.
Application
Apo A-II constitutes ~20% of the protein moiety of high density lipoprotein (HDL).
Biochem/physiol Actions
Unlike Apo A-I, Apo A-II possesses no activating properties for lectin-cholesterol acyltransferase (LCAT). Furthermore, it was found that Apo A-II inhibits the activation of LCAT by Apo A-I.
Physical form
Solution in 10 mM ammonium bicarbonate.
- Related Categories Apolipoproteins, Application Index, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholesterol and Cholesterol Metabolism, Complex Lipids, Enzymes, Inhibitors, and Substrates, Lipids, Lipids in Cell Signaling, Plasma & Blood Proteins, Plasma, Blood, and Related Proteins and Reagents, Proteins and Derivatives, Serum Proteins, Serum Proteins and Related Enzymes More... Quality Level
