Description_x000D_ General description_x000D_ APOA2 stabilizes the HDL structure by its relationship with lipids, and plays a role in the HDL metabolism. APOA2 is the 2nd most abundant protein of the high density lipoprotein particles. 25% of Apo A in HDL is Apo AII. APOA2 is localized in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in APOA2 gene might cause apolipoprotein A-II deficiency or hypercholesterolemia. Levels of Apo AII in normal plasma range from 30-50 mg/100 mL. The physiological role of the protein is unknown. Alcohol consumption, however, increases Apo AII levels._x000D_ Physical form_x000D_ Frozen in 10 mM NH4HCO3, pH 7.4.