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AZASERINE (50X) GAMMA-IRRADIATED CELL CU
Кат. №: A1164
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Description
General description
Chemical structure: amino acid derivatives
Application
For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.
Biochem/physiol Actions
Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.
Reconstitution
Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
- Related Categories Amino Acid Derivatives, Antibiotics, Antibiotics A to Z, Antibiotics by Application, Antibiotics by Mechanism of Action, Antibiotics A-F, Antifungal, Antineoplastic and Immunosuppressive Antibiotics, Biochemicals and Reagents, Cell Culture, Chemical Structure Class, Hybridoma Platform, Hybridoma Reagents, Inhibits an Enzyme, Serum-free Media, Spectrum of Activity More... Quality Level
