Description_x000D_ Application_x000D_ Calycosin, a phytoestrogen isoflavone, may be used to promote and study its mechanisms of angiogenesis via interaction with the estrogen receptor and mitogen-activated protein kinase (MAPK) signaling pathway. Calycosin may be used to study its function and role in neuroprotection via prevention of reperfusion injury. Calycosin may be used as a calcium channel blocker. Calycosin can be used to study its role in protection of HUVECs from advanced glycation end products-induced macrophage infiltration._x000D_ Packaging_x000D_ 10 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Isoflavone and phytoestrogen isolated froma traditional Chinese medicinal herb. Calycosin induces angiogenesis in HUVEC and promotes proliferation of estrogen-receptor positive cells in vivo and in vitro. Also functions as a vasorelaxant on rat thoracic aorta.