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Description_x000D_
General description_x000D_
Chemical structure: ß-lactam_x000D_
Application_x000D_
Cephalothin is a first-generation cephalosporin antibiotic used to study the mechanism of liposome encapsulated antibiotics, strategies for co-opting β-lactamases of Gram-negative bacteria for treatment of antibiotics, and for immunology studies in relation to antibiotics. It is used to study the effect of expression, binding and inhibition of penicillin-binding proteins especially PBP6 on bacterial cell wall mucopeptide synthesis._x000D_
Biochem/physiol Actions_x000D_
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls._x000D_
Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria._x000D_
Mode of Resistance: Production of cephalosporinase will inactivate the product._x000D_
Other Notes_x000D_
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
- Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics by Mechanism of Action, Antibiotics A-F, Biochemicals and Reagents, Chemical Structure Class, Interferes with Cell Wall Synthesis, Penicillins and Cephalosporins (beta-Lactams), Spectrum of ActivityMore... Quality Level