COENZYME A TRILITHIUM SALT

Description_x000D_ General description_x000D_ Coenzyme A (CoA) is synthesized from phosphopantothenate by the action of enzyme pantothenate kinase and is the master regulator._x000D_ Application_x000D_ Coenzyme A trilithium salt has been used:_x000D_ • in standard curve generation in the kinetic assay of acetyltransferase Gcn5 acylation_x000D_ • as a cofactor in JNADH and JNADPH production assay_x000D_ • in the labeling of Alexa647 (AF647) probe_x000D_ Packaging_x000D_ 1 g in poly bottle_x000D_ 10, 25, 100, 500 mg in poly bottle_x000D_ Biochem/physiol Actions_x000D_ Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. Acyl CoA accumulation is implicated in metabolic disorders and may indirectly lead to the pathogenesis associated with carbon-induced mitochondrial stress heart failure, diabetes and obesity._x000D_ Other Notes_x000D_ For more more technical information and a complete list of Coenzyme A deriviatives visit the Acyl Transfer Reagents Resource.