Description_x000D_ Application_x000D_ Cortisone has been used:_x000D_ • to validate a 1β-HSD1 (11β-hydroxysteroid dehydrogenase type 1) inhibitor_x000D_ • to study the sensitivity of erythropoietic and granulopoietic progenitor cells to cortisone_x000D_ • in the determination of rates of cortisol oxidation by 11βHSD_x000D_ Packaging_x000D_ 1, 5 g in glass bottle_x000D_ 250 mg in glass bottle_x000D_ Biochem/physiol Actions_x000D_ Cortisone (11 dehydro 17 hydroxycortico-sterone) is an anti-inflammatory glucocorticoid that delays wound healing after surgeries. It postpones the healing process by affecting the appearance of inflammatory cells, ground substance, fibroblasts, collagen, regenerating capillaries, and epithelial migration. Glucocorticoids have anti-inflammatory, anti-allergic and immunosuppressive properties and are extensively used in treatment and therapy._x000D_ Cortisone is a glucocorticoid; a corticosterone analog that has approximately twice the anti-inflammatory potency as corticosterone but much lower Na2+ retention potency._x000D_ Features and Benefits_x000D_ This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more._x000D_ Packaging_x000D_ Bottomless glass bottle. Contents are inside inserted fused cone._x000D_ Legal Information_x000D_ LOPAC is a registered trademark of Sigma-Aldrich Co. LLC