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DACARBAZINE, ANTINEOPLASTIC PURINE ANAL&
Кат. №: D2390-1G
Цена По запросу
Количество
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Description_x000D_
Application_x000D_
Dacarbazine is a triazine antineoplastic agent that is used for DNA methylation via formation of methyl adducts. It is used to treat metastatic malignant melanomas and Hodgkin′s when used in combination with other antineoplastic agents._x000D_
Packaging_x000D_
1 g in glass bottle_x000D_
100 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
Dacarbazine is a purine analog of naturally occurring purine precursor 5-amino-1H-imidazole-4-carboxamide (AIC). It is a synthetic triazine antineoplastic agent that exerts cytotoxic effects by acting as an alkylating agent and by inhibiting DNA synthesis and inducing apoptosis. It is known to induce hepatotoxicity in mice. Dacarbazine is not cell cycle-phase specific._x000D_
Other Notes_x000D_
Keep container tightly closed in a dry and well-ventilated place.
- Related Categories Antibiotics, Antibiotics A to Z, Antibiotics by Application, Antibiotics by Mechanism of Action, Antibiotics A-F, Antineoplastic and Immunosuppressive Antibiotics, Antitumor Agents, Biochemicals and Reagents, Cancer Research, Cell Biology, DNA Modification / Repair, Interferes with DNA SynthesisMore... Quality Level
