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Daunorubicin hydrochloride, meets USP te
Кат. №: D8809-50MG
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Description_x000D_
Packaging_x000D_
1, 10 mg in glass bottle_x000D_
50 mg in poly bottle_x000D_
Biochem/physiol Actions_x000D_
Naturally fluorescent anthracycline antibiotic, anticancer drug. Substrate for Pgp, MRP-1 and BCRP. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes. Daunorubicin is sequestered into lysosomes according to a pH partitioning type mechanism. Strong inhibitor of DNA and RNA synthesis._x000D_
Potent anticancer agent. Inhibits DNA and RNA synthesis as sequence specific ds-DNA intercalating agent.
- Related Categories Antibiotics, Antibiotics A to Z, Antibiotics by Application, Antibiotics by Mechanism of Action, Antibiotics A-F, Antineoplastic and Immunosuppressive Antibiotics, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Core Bioreagents, Detection and Quantitation, Interferes with DNA Synthesis, Multi-Drug Resistance, Multi-Drug Resistance and Drug Metabolism, Reagents, Research EssentialsMore... Quality Level
