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Description_x000D_
Application_x000D_
Demecolcine has been used as a microtubule depolymerizing agent. It has also been used to inhibit mitotic division._x000D_
Biochem/physiol Actions_x000D_
Often in karyotyping and cell cycle research it is desirable to increase the yield of mitotic cells in a particular phase of the cell cycle. This can be achieved in a variety of ways with the most popular being the use of a cell cycle synchronizing agent such as demecolcine. Demecolcine will arrest cells in metaphase with no remarkable effect on the biochemical events in mitotic cells or in synchronized G1 and S phase cells. White blood cells are often treated with demecolcine to arrest cells in metaphase._x000D_
Packaging_x000D_
Bottomless glass bottle. Contents are inside inserted fused cone.
- Related Categories Apoptosis and Cell Cycle, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix, Inhibitors, Microtubule Inhibitors, Other Apoptosis Related ReagentsMore... Quality Level