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Description_x000D_
Application_x000D_
Dexamethasone has been used:_x000D_
• in culture media to induce differentiation of adipose-derived stem cells into osteogenic tissue_x000D_
• as a component of adipocyte differentiation medium_x000D_
• for in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)_x000D_
Packaging_x000D_
1, 5 g in glass bottle_x000D_
25, 100, 500 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
Dexamethasone is known to be effective against relapsed multiple myeloma. It is found to decrease inflammation associated with cerebrospinal fluid and central nervous system (CNS) complications, such as hearing loss._x000D_
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase._x000D_
Features and Benefits_x000D_
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here._x000D_
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here._x000D_
Packaging_x000D_
Bottomless glass bottle. Contents are inside inserted fused cone._x000D_
Reconstitution_x000D_
Dilute 1 mg/ml stock solution 1:50 with sterile media and store frozen in working aliquots to avoid repeated freeze-thaw.
- Related Categories Application Index, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, D-DIF, Enzymes, Inhibitors, and Substrates, Fluorination Ready Pharma-Developed Compounds, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Merck & Co., Inc., Kenilworth,NJ, Small Molecules for Stem Cell Biology, Stem Cell Biology, Xenobiotics And Drug Metabolism Substrates, Xenobiotics and Drug MetabolismMore... Quality Level