DL-B-HYDROXYBUTYRIC ACID SODIUM &

Description_x000D_ Application_x000D_ DL-β-Hydroxybutyric acid sodium salt has been used:_x000D_ • as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows_x000D_ • to investigate its anticonvulsant effects in epilepsy induced rats_x000D_ • to induce hyperketonemia in Holstein dairy cows_x000D_ Packaging_x000D_ 5, 25, 100 g in poly bottle_x000D_ Biochem/physiol Actions_x000D_ β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).