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Erythromycin, meets USP testing specific
Кат. №: E0774
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Description_x000D_
General description_x000D_
Chemical structure: macrolide_x000D_
Packaging_x000D_
5, 25, 100 g in poly bottle_x000D_
Application_x000D_
Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains._x000D_
Biochem/physiol Actions_x000D_
Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex._x000D_
Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria._x000D_
Caution_x000D_
This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C._x000D_
Preparation Note_x000D_
This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.
- Related Categories A - K, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics by Mechanism of Action, Antibiotics A-F, Biochemicals and Reagents, Chemical Structure Class, Core Bioreagents, Interferes with Protein Synthesis, Macrolides, Pharmacopoeia, Pharmacopoeia A-Z, Pharmacopoeial Antibiotics, Research Essentials, Spectrum of ActivityMore... Quality Level