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G 418 DISULFATE SALT SOLUTION
Кат. №: G8168-100ML
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Description_x000D_
General description_x000D_
Chemical structure: aminoglycoside_x000D_
Application_x000D_
G418 disulfate is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL._x000D_
Biochem/physiol Actions_x000D_
Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes._x000D_
Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes._x000D_
Caution_x000D_
The product is stable for two years when stored at 2-8°C.
- Related Categories A - K, Aminoglycosides, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application, Antibiotics by Mechanism of Action, Antineoplastic and Immunosuppressive Antibiotics, Biochemicals and Reagents, Chemical Structure Class, Core Bioreagents, Genetic Marker Selection, Interferes with Protein Synthesis, Life Science Reagents for Cell Culture, Research Essentials, Spectrum of ActivityMore... Quality Level