GLUTATHIONE-AGAROSE PRE-PACKED COLUMNS (

Description_x000D_ General description_x000D_ The resin in these columns consists of glutathione attached through the sulfur to epoxy activated, 4% cross-linked beaded agarose resulting in a 12 atom spacer._x000D_ Application_x000D_ Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of glutathione binding enzymes such as glutathione-S-transferase, glutathione peroxidase, and glyoxalase I._x000D_ The product was used in the design, synthesis and biological evaluation of new tryptamine and tetrahydro-β-carboline-based selective inhibitors of CDK4. It was also used to study Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1._x000D_ Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of proteins containing glutathione binding sequences, such as Glutathione S-Transferase (GST), glutathione peroxidase and glyoxalase I._x000D_ Linkage_x000D_ Suspension of Product No. G 4510_x000D_ Physical form_x000D_ 1:1 suspension in a 0.5 M NaCl + 20% ethanol solutionl