Description_x000D_ Amino Acid Sequence_x000D_ Gly-Gln_x000D_ General description_x000D_ Glycyl-glutamine (gly-gln) is a dipeptide that is used as a substitute for glutamine in cell culture. Higher cell yields are obtained when this dipeptide is used instead of glutamine, where gly-gln affects substrate utilization and metabolism. Cell growth is higher as the concentrations of this dipeptide remain high, due to lower peptidase affinity._x000D_ Packaging_x000D_ 1, 5 g in glass bottle_x000D_ Application_x000D_ Heat-stable substitute for glutamine in mammalian cell culture media._x000D_ Biochem/physiol Actions_x000D_ Gly-Gln monohydrate has been used for the preparation of glutamine solution in HTF (human tubal fluid) medium to assess the accumulation of ammonium in commercially available culture media and protein supplements for in vitro development of human pre-implantation embryos, when stored at 2–8°C and incubated at 37°C.