GLYCINE, REAGENTPLUS(TM), >= 99% (HPLC)

Description_x000D_ General description_x000D_ Glycine is a non-chiral amino acid. Glycine is a molecule with pI of 6.7, which is similar to the pH of stacking region in polyacrylamide gels. It has advantage of low mobility, hydrophobicity and it does not associate with proteins._x000D_ Application_x000D_ • Glycine has been added in the transfer buffer during western blotting procedure._x000D_ • It has been used in the solution prepared for dissolving formazan crystals in the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) cytotoxicity assay._x000D_ • It has been used for terminating the rat basophilic leukemia (RBL) assay._x000D_ Packaging_x000D_ 1 kg in poly bottle_x000D_ 10 mg in glass bottle_x000D_ 100, 500 g in poly bottle_x000D_ 5, 25 kg in poly drum_x000D_ Biochem/physiol Actions_x000D_ Glycine is an inhibitory neurotransmitter in the central nervous system and works as an allosteric regulator of NMDA (N-methyl-D-aspartate) receptors. It is involved in processing of motor and sensory data, thereby regulating movement, vision and audition._x000D_ Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors._x000D_ Legal Information_x000D_ ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC