Description_x000D_ General description_x000D_ GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed._x000D_ Biochem/physiol Actions_x000D_ GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer._x000D_ Physical form_x000D_ Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT._x000D_ Reconstitution_x000D_ Reconstitute with 100 μL deionized water._x000D_ Other Notes_x000D_ Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.