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L-AZETIDINE-2-CARBOXYLIC ACID
Кат. №: A0760-50MG
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Description
General description
L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.
Application
L-Azetidine-2-carboxylic acid has been used as a:
• collagen synthesis inhibitor
• protein folding antagonist
• as a standard in liquid chromatography-mass spectrometry
Packaging
1 g in poly bottle
50, 100, 250 mg in poly bottle
Biochem/physiol Actions
Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic. It is a four-membered ring analog of L-proline that causes protein misconstruction when incorporated instead of proline.
Features and Benefits
This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.
Legal Information
LOPAC is a registered trademark of Sigma-Aldrich Co. LLC
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