Description_x000D_ General description_x000D_ The ready-to-use MISSION miRNA mimics are small, double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules when introduced into cells. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation. MISSION miRNA Mimics, a member of MISSION RNAi product family, provides miRNA researchers with a range of options from individual MISSION mimics to a full library of human miRNA mimics based on latest version of miRBase (currently hosted by the University of Manchester, previously hosted by the Sanger Institute)._x000D_ • Optimized and ready for transfection._x000D_ • Novel MISSION miRNA mimic design has been functionally tested for knockdown efficiency against natural miRNA targets._x000D_ • Unique MISSION miRNA mimic design significantly reduces possible sense strand off target effects._x000D_ • Available as a whole human library and individual miRNA targets._x000D_ Legal Information_x000D_ MISSION is a registered trademark of Sigma-Aldrich Co. LLC