Description_x000D_ Application_x000D_ N-Nitrosodiethylamine (NDEA) has been used as a hepatocarcinogen/DNA damaging agent. It has been used as a calibration standard for gas–liquid chromatography._x000D_ Packaging_x000D_ 1 g in serum bottle_x000D_ Biochem/physiol Actions_x000D_ N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. It is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. NDEA is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. It results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver._x000D_ Packaging_x000D_ Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal._x000D_ Caution_x000D_ Injecting any compatible solvent permits preparation of any desired strength solution without exposure._x000D_ Reconstitution_x000D_ Dissolving the contents in 100 mL of solvent yields a 1% solution._x000D_ Legal Information_x000D_ Isopac is a registered trademark of Sigma-Aldrich Co. LLC