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NLE-4-D-PHE-7-A-MELANOCYTE STIMULATING H
Кат. №: M8764
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Description_x000D_
Amino Acid Sequence_x000D_
Ac-Ser-Tyr-Ser-Nle-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2_x000D_
General description_x000D_
[Nle4, D-Phe7]-α-melanocyte stimulating hormone is a potent analogue of α;-melanocyte-stimulating hormone (α -MSH). αMSH is a tridecapeptide, mostly produced by the cells in the brain, pituitary and in circulation._x000D_
Application_x000D_
[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt has been used to detect its effect on O2 consumption and CO2 production in C57BL/6 mice.1It is also used to determine its effect on leptin secretion in the primary cultures of differentiated adipocytes._x000D_
Packaging_x000D_
1 mg in glass bottle_x000D_
Biochem/physiol Actions_x000D_
[Nle4, D-Phe7]-α-melanocyte stimulating hormone is 100 times more potent than α-MSH in stimulating melanoma tyrosinase, which is a rate limiting enzyme in melanin biosynthesis and is 26 times as potent as α-MSH in S91adenylate cyclase assay. α –MSH has an essential role to play in melanin production in animals. It also regulates development of several skin diseases, including cutaneous inflammation and hyper-proliferative skin diseases._x000D_
Other Notes_x000D_
Lyophilized from 0.1% TFA in H2O
- Related Categories α-Melanocyte Stimulating Hormone (α-MSH), Cell Biology, Cell Signaling and Neuroscience, Cytokines Growth Factors and Hormones (Obesity), Cytokines, Growth Factors and Hormones, Hormones, Immunomodulators, Ion Channel Modulating Peptides, Melanocyte Stimulating Hormone (MSH), Melanocyte Stimulating Hormones (MSH), Obesity Research, Peptides and Proteins, Peptides for Cell Biology, Pituitary HormonesMore... Quality Level